Nanoscale detection of metal-labeled copolymers in patchy polymersomes
نویسندگان
چکیده
منابع مشابه
Polymersomes: tough vesicles made from diblock copolymers.
Vesicles were made from amphiphilic diblock copolymers and characterized by micromanipulation. The average molecular weight of the specific polymer studied, polyethyleneoxide-polyethylethylene (EO40-EE37), is several times greater than that of typical phospholipids in natural membranes. Both the membrane bending and area expansion moduli of electroformed polymersomes (polymer-based liposomes) f...
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Polymer vesicles, or polymersomes, are promising candidates for applications in drug delivery and tissue imaging. While a vast variety of polymers have been explored for their ability to assemble into polymersomes, relatively little research on the functionalization of these polymers has been reported. We present here a novel route for the synthesis of poly(caprolactone)-b-poly(ethylene glycol)...
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Hierarchical biological systems such as tissues and organs are often characterised by highly crowded and packed environments with nanoscopic interconnections between them. Engineering nanovectors that can penetrate and diffuse across these is critical to ensure enhanced delivery and targeting. Here we demonstrate that flexible polymeric vesicles, known as polymersomes, enable the translocation ...
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Purpose: Enalapril maleate (EPM), was used for hypertension and congestive heart failure. In this way, an innovative delivery system with mPEG–PCL was synthesized and the release profile of the EPM from the drug-loaded polymersomes was evaluated. Methods: Di-block methoxy)-poly (ethylene glycol) - Poly (caprolactone) (mPEG-PCL) copolymers were synthesized and used to prepare of polymersom...
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Mass transport processes on metal surfaces play a key role in epitaxial growth and coarsening processes. They are usually described in terms of independent, statistical diffusion and attachment/detachment of individual metal adatoms or vacancies. Here we present high-speed scanning tunnelling microscopy (video-STM) observations of the dynamic behaviour of five-atom-wide, hexagonally ordered str...
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ژورنال
عنوان ژورنال: Polymer Chemistry
سال: 2015
ISSN: 1759-9954,1759-9962
DOI: 10.1039/c4py01508h